At the beginning of 2020, COVID-19 became a global problem. Despite all the efforts to emphasize the relevance of preventive measures, not everyone adhered to them. Thus, learning more about the characteristics determining attitudinal and behavioral responses to the pandemic is crucial to improving future interventions. In this study, we applied machine learning on the multi-national data collected by the International Collaboration on the Social and Moral Psychology of COVID-19 (N = 51,404) to test the predictive efficacy of constructs from (...) social, moral, cognitive, and personality psychology, as well as socio-demographic factors, in the attitudinal and behavioral responses to the pandemic. The results point to several valuable insights. Internalized moral identity provided the most consistent predictive contribution—individuals perceiving moral traits as central to their self-concept reported higher adherence to preventive measures. Similar was found for morality as cooperation, symbolized moral identity, self-control, open-mindedness, collective narcissism, while the inverse relationship was evident for the endorsement of conspiracy theories. However, we also found a non-negligible variability in the explained variance and predictive contributions with respect to macro-level factors such as the pandemic stage or cultural region. Overall, the results underscore the importance of morality-related and contextual factors in understanding adherence to public health recommendations during the pandemic. (shrink)

Moral judgments can occur either in settings that call for impartiality or in settings that allow for partiality. How effective are impartiality settings such as hospitals in suppressing personal biases? Portrayed as decision-makers in an emergency department, 431 college students made judgments on which of two victims of a mass shooting should receive immediate, life-saving care. Patients differed in ways that could reveal biases, e.g., age, kinship, gender, and villain/hero. Participants rated each patient’s moral deservingness to receive immediate care and (...) the likelihood they would choose the patient. Both scales showed young favored over old, cousin over stranger, and policeman over shooter. In a hospital-room scenario with high risk of injury from falling, age bias disappeared. With moderate fall risk, age bias reversed and kinship deservingness bias disappeared. Bias decreases when there is a decrease in severity of potential harm to the preferred stakeholder. Settings that call for impartiality are not reliable “boundary conditions” against expressions of bias. In the absence of explicit guidelines for allocating scarce resources, a systematic, objective method of random selection offers a potentially useful strategy. (shrink)

Electrical resistivity and ac-calorimetric measurements reveal a complex magnetic phase diagram for single crystals of the ferromagnetic Kondo-lattice compound CeAgSb2 at high pressures up to 80 kbar. The ferromagnetic order at TC = 9.6 K at ambient pressure is completely suppressed at a critical pressure PC = 35 kbar. Another magnetic transition, possibly antiferromagnetic, found above 27 kbar, attains a maximum value TN 6 K at 44 kbar and then appears to be completely suppressed by 50 kbar. Thermodynamic and transport (...) measurements in the ferromagnetic state indicate an energy gap Δ 30 K in the spin-wave excitation spectrum at ambient pressure which decreases to Δ 10 K at P = 30 kbar. No superconductivity is observed at ambient pressure above T 0.1 K, under applied pressure in the ferromagnetic state (P = 28.5 kbar), nor in the antiferromagnetic state (P = 33 − 46 kbar) above 0.3 K. © 2003 The American Physical Society. (shrink)

Participants acting as mock jurors made inferences about whether a person was a suspect in a murder based on an expert's testimony about the presence of objects at the crime scene and the disclosure that the testimony was true or false. Experiment 1 showed that participants made more correct inferences, and made inferences more quickly, when the truth or falsity of the expert's testimony was disclosed immediately after the testimony rather than when the disclosure was delayed. Experiment 2 showed no (...) advantage for prior disclosure over immediate disclosure. Experiment 3 showed that the pattern of inferences when there was no disclosure mirrored the pattern when it was disclosed that the expert's testimony was true rather than false. Participants made more correct inferences from true conjunctions than disjunctions, and from false disjunctions than conjunctions. We discuss the implications for theories of the mental representations and cognitive processes that underlie human reasoning. (shrink)

This paper analyses the details that characterized the negotiation and collection of the servicio de los naturales from the year 1603 onwards, the last time of those three in which moriscos of Granada paid to the Hispanic Monarchy after the Alpujarras War, when they were settled in Castile. The author has analysed documents coming from the Archivo General de Simancas, but also those included in notary’s protocols and in local archives. Its main contributions are three: to publish the content of (...) the actual contract signed by the moriscos and the Crown; to contribute to set up a precise spatial distribution of the communities that paid the tax and, finally, to show the amounts delivered by them. Irregularities, problems, and conflicts lived while the precedent servicios were being paid, are analysed too. There are aspects that we know thanks to other previous works. Nevertheless, if they are considered in relation with the situation of the year 1603, they allow observing that all those difficulties were used in order to improve the servicio itself and the agreement between the minority and the King. (shrink)

Crisis requires society to renew itself, albeit in a disruptive way. The current Covid-19 pandemic is transforming ways of working, living, and relating to each other on a global level, suddenly and dramatically. This paper focuses on the field of education to show how higher education institutions are undergoing radical transformations driven by the need to digitalize education and training processes in record time with academics who lack innate technological capabilities for online teaching. The university system must strive to overcome (...) this situation to be competitive and provide high-quality education in a scenario of digital transformation, disruptive technological innovations, and accelerated change. To achieve these goals, this paper explains some barriers and challenges that universities encounter, as well as technological resources and methodologies they have used in the current scenario to transform higher education to face Covid-19 disruption. The discussion and conclusion synthesize significant insights that can be applied to the digitalization of education in the foreseeable future. (shrink)

El presente estudio muestra la opinión de estudiantes universitarios del Grado en Maestro en Educación Primaria en relación al uso de recursos audiovisuales, concretamente el vídeo, para el aprendizaje del método científico en la etapa de Educación Primaria. Se realiza un cuestionario, antes y después de la actuación y se comparan los datos a través del programa estadístico SPSS v.26. Los datos arrojan que existen diferencias significativas en cuestiones como la utilidad para los docentes, la inclusión o para trabajar la (...) educación medioambiental. Además, se produce un avance de las medias (no significativo) en las demás cuestiones planteadas. (shrink)

Human Resources Practices and unions coexist in some organisations to manage the employment relationships of the workers. In this study, we analyse how the presence/absence of unions and HRPs are combined in private European organisations, and which of these combinations are related to higher levels of wellbeing and the quality of labor relations. Data come from 24,503 workers of private organisations, obtained from the Sixth European Working Conditions Survey. Latent profiles analysis and different analyses of the variance suggested four different (...) profiles. The profile with the greatest presence of HRPs and union presence is related to the highest levels of employees' wellbeing and quality of labor relations in organisations, whereas those organisations with a low level of union presence or HRPs reached the worst levels in employees' wellbeing and quality of labor relations indicators. The results and their practical implications are discussed. (shrink)

In recent decades, the expansion of economic activity has been accompanied by negative environmental impacts. In response, there have been dramatic changes worldwide in terms of an increased demand for environmentally friendly products and services. To achieve these eco-innovations, firms have sought to acquire knowledge and implement operational flexibility by cooperating with different agents such as universities through a value cocreation system that is also expected to enhance firms’ performance. Using a sample of 250 companies, the present paper examines the (...) role of cooperation with universities in the development of diverse environmental innovations and building operational flexibility and, through this, improving firm performance. Results show that firms that value cooperation with universities develop a wider range of environmental innovations and increase their sales and benefits. (shrink)

Abstract“The Book of Secrets in the Results of Ideas”, usually called “The Book of Secrets” is a codex containing drawings and descriptions of thirty-one artifacts attributed to the engineer Alī Ibn Khalaf al-Murādī, who lived in Andalusia in southern Spain at the beginning of the 11th century. This manuscript is one of the first written testimonies that describe medieval mechanisms with complex precision. The aim of this work is to reconstruct and study from a historical and technological point of view (...) two of the ancient artifacts contained in the “Book of Secrets”, the “Fortress Demolisher” and the “Magic Well”. The “Fortress Demolisher” is a war machine designed to demolish the upper part of the walls or towers and consists of a battering ram mounted on a platform that can be raised several meters above the ground using a scissor mechanism. The “Magic Well” is a mechanism with several pulleys whose purpose is to raise water several meters from the bottom of a well by collecting a small portion of rope. To reconstruct the two artifacts, a digital model and a detailed study of the geometry and operation of the mechanisms, were first carried out. 3D printing, using the Fused Deposition Modelling technology, made the physical reproduction. The digitization and physical reproduction by 3D printing of the mechanisms represent an update of the traditional ways of transmitting knowledge. The use of these new technologies makes the knowledge more accessible, understandable and attractive. (shrink)

Public health ethics, like the field of public health it addresses, traditionally has focused more on practice and particular cases than on theory, with the result that some concepts, methods, and boundaries remain largely undefined. This paper attempts to provide a rough conceptual map of the terrain of public health ethics. We begin by briefly defining public health and identifying general features of the field that are particularly relevant for a discussion of public health ethics.Public health is primarily concerned with (...) the health of the entire population, rather than the health of individuals. Its features include an emphasis on the promotion of health and the prevention of disease and disability; the collection and use of epidemiological data, population surveillance, and other forms of empirical quantitative assessment; a recognition of the multidimensional nature of the determinants of health; and a focus on the complex interactions of many factors—biological, behavioral, social, and environmental—in developing effective interventions. (shrink)

Ethical approval must be obtained before medical research can start. We describe the differences in EA for an pseudonymous, non-interventional, observational European study. Sixteen European national coordinators of the international study on very old intensive care patients answered an online questionnaire concerning their experience getting EA. N = 8/16 of the NCs could apply at one single national ethical committee, while the others had to apply to various regional ECs and/or individual hospital institutional research boards. The time between applying for (...) EA and the first decision varied between 7 days and 300 days. In 9/16 informed consent from the patient was not deemed necessary; in 7/16 informed consent was required from the patient or relatives. The upload of coded data to a central database required additional information in 14/16. In 4/16 the NCs had to ask separate approval to keep a subject identification code list to de-pseudonymize the patients if questions would occur. Only 2/16 of the NCs agreed that informed consent was necessary for this observational study. Overall, 6/16 of the NCs were satisfied with the entire process and 8/16 were unsatisfied. 11/16 would welcome a European central EC that would judge observational studies for all European countries. Variations in the process and prolonged time needed to get EA for observational studies hampers inclusion of patients in some European countries. This might have a negative influence on the external validity. Further harmonization of ethical approval process across Europe is welcomed for low-risk observational studies. Getting ethical approval for low-risk, non-interventional, observational studies varies enormously across European countries. (shrink)

The acquisition and evolution of speech production, discourse and communication can be negatively impacted by brain malformations. We describe, for the first time, a case of developmental dynamic dysphasia (DDD) in a right-handed adolescent boy (subject D) with cortical malformations involving language-eloquent regions (inferior frontal gyrus) in both the left and the right hemispheres. Language evaluation revealed a markedly reduced verbal output affecting phonemic and semantic fluency, phrase and sentence generation and verbal communication in everyday life. Auditory comprehension, repetition, naming, (...) reading and spelling were relatively preserved, but executive function was impaired. Multimodal neuroimaging showed a malformed cerebral cortex with atypical configuration and placement of white matter tracts bilaterally and abnormal callosal fibers. Dichotic listening showed right hemisphere dominance for language and functional magnetic resonance imaging (fMRI) additionally revealed dissociated hemispheric language representation with right frontal activation for phonology and bilateral dominance for semantic processing. Moreover, subject D also had congenital mirror movements (CMM), defined as involuntary movements of one side of the body that mirror intentional movements of the other side. Transcranial magnetic stimulation and fMRI during voluntary unimanual (left and right) hand movements showed bilateral motor cortex recruitment and tractography revealed a lack of decussation of bilateral corticospinal tracts. Genetic testing aimed to detect mutations that disrupt the development of commissural tracts correlating with CMM (e.g., Germline DCC mutations) was negative. Overall, our findings suggest that DDD in subject D resulted from the underdevelopment of the left inferior frontal gyrus with limited capacity for plastic reorganization by its homologous counterpart in the right hemisphere. Corpus callosum anomalies probably contributed to hinder interhemispheric connectivity necessary to compensate language and communication deficits after left frontal involvement. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:FINALITY AND INTELLIGIBILITY IN BIOLOGICAL EVOLUTION ANTONIO MORENO, O.P. Graduate Theological Union Berkeley, California I N SCIENCE AND philosophy the final cause has always..,been controversial. To biologists the problem is complicated, but many believe that it is impossible fo give a complete description of the phenomenon of life without taking into oonsideration the teleological aspect of it. Thus Rensch: A special feature of all living organisms is the (...) fact that biological processes in general appear to be: 'meaningful.' They are not only appropriate to the immediate conditions, but also seem to be directed to some purpose which in individual development is only achievE:d at a relatively late stage and after many modications of form.1 Simpson's approach to this problem is shaped by the conviction that biology should attempt to answer all the questions, one of whioh is the reason for a living being's activity: "Here, ' What for '-the dreadful teleological question-not only is legitimate but also must eventually be asked about every vital phenomenon." 2 To understand how finality is realized in biology, let us first turn briefly to the nature of the final cause. The Nature of the Final CaU8e Aristotle deals with causes in the seeond book of his Physics: It is through the causes that scientific conclusions about mobile heings are demonstrated. Movement is intelligible when we discover the causes that produce it. Among the 1B. Rensch, Biophilosophy (New York: Columbia University Press, 1971), p. 107. 2 G. Simpson, Th,is Vi.ew of Life (New York: Ifarcourt, 1964),.pp. 104-108. l ANTONIO MORENO, O.P. causes, the first and most important is the final cause, which is defined as "that for the sake of which a thing is done." 3 The final cause is the motive or reason which impels the agent to operate. Motion is the vehicle by whioh the goal is attained and, consequently, the other causes exercise their causality in dependence on the final cause. Hence, Aquinas says: " The final cause is called the cause of causes, because it is the cause of the causality of all the causes. For it is the cause of the efficient ca:usality; and the efficient cause is the cause of the causality of both the matter and the form.".j, The final cause directs, inclines, and attracts; impelled by this attraction, the efficient pushes and exercises its action. Aquinas asserts that those who reject the final cause destroy the intelligibility of science, inasmuch as they suppress the motive or first reason which justifies motion. The final cause is not the cause that executes the adion, for this is the agent's function, the efficient cause. The final cause is the reason why the agent acts. Therefore, the efficient cause presupposes the final: "The end is not the cause unless it moves the agent to act. If there is no action the final cause does not exist." 5 It is interesting to note that many biologists believe that the existence of finality destroys causality, when actually the opposite is true. For example, Simpson says: " The finalist was often the man who made a liberal use of ignaV'a ratio,... when you failed to explain a, thing by the ordinary process of causality, you could ' explain ' it 1by reference to some purpose of nature." 6 A simple desirn or attraction is not a cause unless it is fol3 Aristotle, Ph&sias (Trans. W. D. Ross) Book II, 3, 194b34. (Oxford, 1962). 4 Thomas Aquinas, In V Metaph., Iect. 3, n. 782. Of. Summa Theol., I, q. 105, a.5. 5 Thomas Aquinas, On the Power of God, trans. English Dominican Fathers (Westminster, Md.: Newman Press, 1952), q.5, a. l. 6 G. Simpson, The Meaning of Evolution (New Haven: Yale University Press, 1967), p. 274. FINALITY IN BIOLOGICAL EVOLUTION 3 lowed by the activity of the agent. The desire to attain the goal is called the " intention " of the action, even when the goal is not achieved, as happens in many of our actions. Failure does not destroy finality; inactivity does. For that which is first in the intention is the last to be achieved as the effect. The intention does not... (shrink)

This essay aims to show that a phenomenological account of animal behavior can shed light on an ethological approach to alterity, and vice versa. The interface between ethology and phenomenology–which, as it is argued, is intelligible only with reference to a shared dimension of affection–is framed by means of the phenomenological concept of intentionality, which appears as a generative force of the organism, its behavior and surrounding world. This means that intentionality does not shape stable structures, but plastic and dynamic (...) processes that bound both the genesis of an organism and its surrounding world. Formation is thus understood as an epigenetic development, which suggests that natural forms are the result of a movement that goes from the general to the particular, from the most broad and regular structures of experience, to the multifarious proliferation of perspectives. (shrink)

Je rappelle ici l’une des plus constantes préoccupations de la pensée de Jean-Luc Nancy : celle du destin d’un Occident qui, au moment même où il paraît accomplir son élargissement au monde entier, est amené à faire, de plus en plus, le constat de son propre effacement, de son déclin, ou de sa finitude. Je le fais tout en déplaçant quelque peu le point de vue d’où le problème se pose « normalement » car, comme c’est arrivé maintes fois dans (...) mes échanges avec Nancy lui-même, j’y fais jouer mon écart, ou mon arrabal hispanique. (shrink)

El artículo aborda la fenomenología de la donación de Marion, especialmente por lo que se refiere a la crítica a la metafísica implícita en la defensa de la relevancia del fenómeno saturado, a fin de vislumbrar que aquella fenomenología no restringe su validez a aquella que podría concederle una experiencia en el horizonte de acontecimientos extraordinarios y, en concreto, de fe religiosa, lo que favorecería pensar que la donación tiene un alcance solo parcial y restringido (en el contexto del giro (...) teológico de la fenomenología francesa), y por tanto meramente regional, incluso sobre todo subjetivo. A modo de sugerencia, se propondrá aquí como hipótesis que, más allá de la diferencia ostensible entre Marion y Bataille, entre la experiencia de la donación y la experiencia interior de uno y otro, respectivamente, se puede descubrir una comunidad de base y fondo que precisamente puede ser esclarecida por la fenomenología de la donación, demostrándose así que ésta no encuentra su legitimidad meramente en el territorio del fenómeno de revelación (fe) ni en el extremismo de la donación, habiéndose Marion ya esforzado, en otro de los frentes críticos que ha debido abordar, en pensar la saturación de “baja intensidad” o banal. (shrink)

The divine attributes of omniscience and omnipotence have faced objections to their very consistency. Such objections rely on reasoning parallel to semantic paradoxes such as the Liar or to set-theoretic paradoxes like Russell's paradox. With the advent of paraconsistent logics, dialetheism—the view that some contradictions are true—became a major player in the search for a solution to such paradoxes. This paper explores whether dialetheism, armed with the tools of paraconsistent logics, has the resources to respond to the objections levelled against (...) the divine attributes. (shrink)

Although there are many different philosophical hares that could be started by the use of the term ‘historical fact’ I am interested in pursuing one that is related to the historian's attitude to testimony. By way of preliminary, however, I should say something about my use of the word ‘fact’. A contrast that sets off my use best is probably that between fact and theory. This distinction is at once methodological and epistemological in that it concerns the structure of inquiry (...) as well as the structure of secure belief. As far as inquiry is concerned it is plausible to suppose that an investigation begins with a problem or a puzzle, the delineation of which requires certain data in the form of propositions that are known to be true, or are taken for granted or commonly agreed upon as sufficiently secure to provide a grounding for the inquiry. It is to cover such data that I am using the word ‘fact’ and hence it will not refer to just any true proposition. Theories however stand as the outcome of inquiry and involve generality and inference and classification in a way that facts do not. It is interesting that the term ‘datum’ came into use in English at the same time that the word ‘fact’, which had meant ‘a deed or action’, acquired the sort of meaning that interests me here. (shrink)

Marion Lee Sanders,1 Anthony James Langone2 1Department of Medicine, Division of Nephrology and Hypertension, University of Iowa, Iowa City, IA, 2Department of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, TN, USA: Transplantation is the preferred treatment option for individuals with end-stage renal disease. Individuals who undergo transplantation must chronically be maintained on an immunosuppression regimen for rejection prophylaxis to help ensure graft survival. Current rejection prophylaxis consists of using a combination of calcineurin inhibitors, mTOR inhibitors, antimetabolite (...) agents, and/or corticosteroids. These agents have collectively improved the short-term outcomes of renal transplantation, but improvements in late/chronic graft loss and recipient survival have lagged significantly behind challenging the field of transplantation to develop novel prophylactic agents. There have been several clinical trials conducted within the last 5 years in an attempt to bring such novel agents to the commercial market. These trials have resulted in the US Food and Drug Administration approval of extended-release tacrolimus, as well as belatacept, which has the potential to replace calcineurin inhibitors for rejection prophylaxis. Other trials have focused on the development of novel calcineurin inhibitors, costimulation blockade, kinase inhibitors, and inhibitors of leukocyte migration. While these later agents have not been FDA-approved for use in transplantation, they remain noteworthy, as these agents explore pathways not previously targeted for allograft-rejection prophylaxis. The purpose of this review was to consolidate available clinical trial data with regard to the recent developments in rejection prophylaxis in kidney transplantation. Keywords: rejection, prophylaxis, immunosuppression, transplantation. (shrink)

The author deals with the meaning of metamerism. Two contrary points of view may serve to clear the problem. From the morphological point of view probably outgrowth of the organism in longitudinal direction has led to the development of metameres. So the first segmentation is due to a functional differentiation. In Phylogeny this segmentation has been maintained and the originally developed metameres remain the primary morphotic units of the organisms. Further specialising of function and organ-concentration destroyed the original absolute metamerism (...) and only left a rest of the original.The functional point of view renounces an original absolute metamerism for the present moment. It only asks for the functional meaning of the segmentation in organisms, showing this segmentation. From the functional point of view it is possible that metamerism may be the morphological expression of quite different functional requirements and that in one organism the metamerism starts from another system of organs than in another.Es wird gefragt welche Bedeutung die Metamerie haben kann. Zur Erläuterung des Problems werden zwei extremen Betrachtungsweisen einander gegenübergestellt. Nach der morphologischen Betrachtungsweise hat Wachstum der Organismen in die Länge wahrscheinlich zur Ausbildung der Metamerie geführt. Diese erste Metamerie ist wahrscheinlich ein funktioneller Differenzierungsprozess gewesen.In der Phylogenese hat sich diese Metamerie behauptet und die ursprünglich entstandene Metamere sind die primären morphotischen Einheiten der Organismen geblieben. Weitergehende Funktionsspezialisierung und Organkonzentration hat die ursprüngliche absolute Metamerie vernichtet. Was davon übrig blieb sind die Reste der ursprünglichen.Die funktioneile Betrachtungsweise verzichtet vorläufig auf eine ursprüngliche absolute Metamerie. Sie fragt bloss nach der funktionellen Bedeutung, welche die Metamerie besitzt bei denjenigen Organismen, wo diese gefunden wird. Sie achtet es möglich, dass Metamerie der Ausdruck sein kann von ganz verschiedenen funktionellen Anforderungen und dass somit die Metamerie bei der einen Tiergruppe von einem ganz anderen Organsystem ausgeht wei bei einer anderen. (shrink)

The crux of this book is expressed in one short sentence from the Preface: 'Unity is a fundamental part of our experience, something that is crucial to its phenomenology' [p.xii], and the crux of this sentence is that the unity of consciousness is not a matter of phenomenal relations existing between distinct experiences – the received view [p.17], but the existence of relations between the contents of experiences – the one experience view [p.25ff]. In its simplest form Tye's claim is (...) that: all our conscious states, whether visual, auditory, olfactory, tactual or gustatory, whether imagistic or emotional are experienced concurrently; they 'are phenomenologically unified ... [and] ... Phenomenological unity is a relation between qualities represented in experience, not between qualities of experiences. [p.36]. (shrink)

Cancer is a complex disease, necessitating research on many different levels; at the subcellular level to identify genes, proteins and signaling pathways associated with the disease; at the cellular level to identify, for example, cell-cell adhesion and communication mechanisms; at the tissue level to investigate disruption of homeostasis and interaction with the tissue of origin or settlement of metastasis; and finally at the systems level to explore its global impact, e.g. through the mechanism of cachexia. Mathematical models have been proposed (...) to identify key mechanisms that underlie dynamics and events at every scale of interest, and increasing effort is now being paid to multi-scale models that bridge the different scales. With more biological data becoming available and with increased interdisciplinary efforts, theoretical models are rendering suitable tools to predict the origin and course of the disease. The ultimate aims of cancer models, however, are to enlighten our concept of the carcinogenesis process and to assist in the designing of treatment protocols that can reduce mortality and improve patient quality of life. Conventional treatment of cancer is surgery combined with radiotherapy or chemotherapy for localized tumors or systemic treatment of advanced cancers, respectively. Although radiation is widely used as treatment, most scheduling is based on empirical knowledge and less on the predictions of sophisticated growth dynamical models of treatment response. Part of the failure to translate modeling research to the clinic may stem from language barriers, exacerbated by often esoteric model renderings with inaccessible parameterization. Here we discuss some ideas for combining tractable dynamical tumor growth models with radiation response models using biologically accessible parameters to provide a more intuitive and exploitable framework for understanding the complexity of radiotherapy treatment and failure. (shrink)

What can literary education contribute to moral education? In this article the inherent practical, moral or political, relevance of literature and literary education is defended, which is opposed to a moralist approach to (children's) literature. A much debated danger in literature and the arts, viz. that it gives rise to a flight into a "promised land" instead of having relevance for real life and the real world, can be overcome by bringing to the fore the active part the reader plays (...) in realizing the "world of the work." The classical idea of mimesis (i.e. of art mirroring reality) then makes room for a historicity of reading with an ongoing interplay of the (real) worlds of readers and the (fictive) world of the text. This idea is elaborated on from the point of view of Ricoeur's hermeneutics and from that of Iser's reception aesthetics, respectively. In realizing the world of the work the world of the reader is transcended and opened up towards the possible. In this reconfiguration lies the practical relevance of literature. Books, therefore, do not have to mirror the actual world in order to be morally or politically relevant. It is in the act of reading that the lasting significance of so-called classics is renewed time and time again. (shrink)